SKINTEGRITY.CH Principal Investigators are in bold
Ben-Yehuda Greenwald, M., Liu, Y.H., Li, W., Hiebert, P., Zubair, M., Tenor, H., Braun, T., Naef, R., Razansky, D., & Werner, S. (2022). Topical wound treatment with a nitric oxide-releasing PDE5 inhibitor formulation enhances blood perfusion and promotes healing in mice. Pharmaceutics, 14(11), 2358. DOI 10.3390/pharmaceutics14112358
Cangkrama, M., Liu, H., Whipman, J., Zubair, M., Matsushita Azuma, M., Kopf, M., Innocenti, M., & Werner, S. (2022). A pro-tumorigenic mDia2-MIRO1 axis controls mitochondrial positioning and function in cancer-associated fibroblasts. Cancer Res, 82(20), 3701-17. DOI 10.1158/0008-5472.CAN-22-0162
Di Filippo, M., Hennig, P., Karakaya, T., Slaufova, M., & Beer, H. D. (2022). NLRP1 in Cutaneous SCCs: An Example of the Complex Roles of Inflammasomes in Cancer Development. Int J Mol Sci, 23(20), 12308. DOI 10.3390/ijms232012308
Fenini, G., Karakaya, T., Hennig, P., Di Filippo, M., Slaufova, M., & Beer, H. D. (2022). NLRP1 inflammasome activation in keratinocytes: increasing evidence of important roles in inflammatory skin diseases and immunity. J Invest Dermatol, 142(9), 2313. DOI 10.1016/j.jid.2022.04.004
Guendisch, U., Loos, B., Cheng, P. F., Dummer, R., Levesque, M. P., Varum, S., & Sommer, L. (2022). Loss of YY1, a Regulator of Metabolism in Melanoma, Drives Melanoma Cell Invasiveness and Metastasis Formation. Front Cell Dev Biol, 10(916033), 1152. DOI 10.3389/fcell.2022.916033
He, Y., Kim, J., Tacconi, C., Moody, J., Dieterich, L. C., Anzengruber, F., Maul, J.-T., Gousopoulos, E., Restivo, G., Levesque, M.P., Lindenblatt, N., Shin, J.W., Hon, C.-C., & Detmar, M. (2022). Mediators of capillary-to-venule conversion in the chronic inflammatory skin disease psoriasis. J Invest Dermatol, in press. DOI 10.1016/j.jid.2022.05.1089
He,Y., Tacconi, C., Dieterich, L.C., Kim, J., Restivo, G., Gousopoulos, E., Lindenblatt, N., Levesque, M.P., Claassen, M., & Detmar, M. (2022). Novel blood vascular endothelial subtype-specific markers in human skin unearthed by single-cell transcriptomic profiling. Cells, 11(7), 1111. DOI 10.3390/cells11071111
Hennig, P., Di Filippo, M., Bilfeld, G., Mellett, M., & Beer, H.D. (2022). High p62 expression suppresses the NLRP1 inflammasome and increases stress resistance in cutaneous SCC cells. Cell Death Dis, 13(12), 1077. DOI 10.1038/s41419-022-05530-0
Hiebert, P., Martyts, A., Schwestermann, J., Janke, K., Hafner, J., Boukamp, P., Mazza, E. & Werner, S. (2022). Nrf2 promotes skin fragility via mRNA-mediated collagen targeting and activation of the aging matrisome. Matrix Biol, 113, 39. DOI 10.1016/j.matbio.2022.09.002
Kaeser-Pebernard, S., Vionnet, C., Mari, M., Sankar, D. S., Hu, Z., Roubaty, C., Martínez-Martínez, E., Zhao, H., Spuch-Calvar, M., Petri-Fink, A., Rainer, G., Steinberg, F., Reggiori, F., & Dengjel, J. (2022). mTORC1 controls Golgi architecture and vesicle secretion by phosphorylation of SCYL1. Nat Commun, 13(4685), 1-21. DOI 10.1038/s41467-022-32487-7
Kim, J., He, Y., Tormen, S., Kleindienst, P., Restivo, G., Drach, M., Levesque, M.P., Navarini, A.A., Tacconi, C., & Detmar, M. (2022) The p300/CBP inhibitor A485 normalizes psoriatic fibroblast gene expression in vitro and reduces psoriasis-like skin inflammation in vivo. J Invest Dermatol, JID 3571. DOI 10.1016/j.jid.2022.09.004
Koch, M., Kockmann, T., Rodriguez, E., Wehkamp, U., Hiebert, P., Ben-Yehuda Greenwald, M., Stölzl, D., Beer, H.-D., Tschachler, E., Weidinger, S., Werner, S., & auf dem Keller, U. (2022). Quantitative proteomics identifies reduced NRF2 activity and mitochondrial dysfunction in Atopic Dermatitis. J Invest Dermatol, in press. DOI 10.1016/j.jid.2022.08.048
Krzywinska, E., Sobecki, M., Nagarajan, S., Zacharjasz, J., Tambuwala, M. M., Pelletier, A., Cummins, E., Gotthardt, D., Fandrey, J., Kerdiles, Y.M., Peyssonnaux, C., Taylor, C.T., Sexl, V., & Stockmann, C. (2022). The transcription factor HIF-1α mediates plasticity of NKp46+ innate lymphoid cells in the gut. J Exp Med, 219(2), e20210909. DOI 10.1084/jem.20210909
Liu, Y.H., Brunner, L.M., Rebling, J., Ben-Yehuda Greenwald, M., Werner, S., Detmar, M., & Razansky, D. (2022). Non-invasive longitudinal imaging of VEGF-induced microvascular alterations in skin wounds. Theranostics, 12(2), 558-573. DOI 10.7150/thno.65287
Luo, X.G., Kuipers, J., & Beerenwinkel, N. (2022). Joint inference of repeated evolutionary trajectories and patterns of clonal exclusivity or co-occurrence from tumor mutation trees. Preprint, DOI 10.1101/2021.11.04.467347
Martínez-Martínez, E., Atzei, P., Vionnet, C., Roubaty, C., Kaeser-Pebernard, S., Naef, R., & Dengjel, J. (2022). A Dual-Acting Nitric Oxide Donor and Phosphodiesterase 5 Inhibitor Activates Autophagy in Primary Skin Fibroblasts. Int J Mol Sci, 23(12), 6860. DOI 10.3390/ijms23126860
Pontiggia, L., Ahuja, A. K., Yosef, H. K., Rütsche, D., Reichmann, E., Moehrlen, U., & Biedermann, T. (2022). Human basal and suprabasal keratinocytes are both able to generate and maintain dermo–epidermal skin substitutes in long-term in vivo experiments. Cells, 11(14), 2156. DOI 10.3390/cells11142156
Pontiggia, L., Van Hengel, I. A., Klar, A., Rütsche, D., Nanni, M., Scheidegger, A., Figi, S., Reichmann, E., Moehrlen, U., & Biedermann, T. (2022). Bioprinting and plastic compression of large pigmented and vascularized human dermo-epidermal skin substitutes by means of a new robotic platform. J Tissue Eng, 13(20417314221088513). DOI 10.1177/20417314221088513
Restivo , G., Tastanova, A., Balázs, Z., Panebianco, F., Diepenbruck, M., Ercan, C., Preca, B.T., Hafner, J., Weber, W.P., Kurzeder, C., Vetter, M., Münst Soysal, S., Beisel, C., Bentires-Alj, M., Piscuoglio, S., Krauthammer, M., & Levesque, M.P. (2022). Live slow-frozen human tumor tissues viable for 2D, 3D, ex vivo cultures and single-cell RNAseq. Commun biol, 5(1), 1-12. DOI 10.1038/s42003-022-04025-0
Sanchez-Macedo, N., McLuckie M., Grünherz, L., & Lindenblatt, N. (2022). Protein profiling of mechanically processed lipoaspirates: discovering wound healing and anti-fibrotic biomarkers in nanofat. Plast Reconstr Surg, 10.1097(9345). DOI 10.1097/prs.0000000000009345
Sobecki, M., Chen, J., Krzywinska, E., Nagarajan, S., Fan, Z., Nelius, E., Monné Rodriguez, J.M., Seehusen, F., Hussein, A., Moschini, G., Hajam, E.Y., Kiran, R., Gotthardt, D., Debbache, J., Badoual, C., Sato, T., Isagawa, T., Norihiko, T., Tanchot, C., Tartour, E., Weber, A., Werner, S., Loffing, J., Sommer, L., Sexl, V., Münz, C., Feghali-Bostwick, C., Pachera, E., Distler, O., Snedeker, J., Jamora, C., & Stockmann, C. (2022). Vaccination-based immunotherapy to target profibrotic cells in liver and lung. Cell Stem Cell, 29, 1459. DOI 10.1016/j.stem.2022.08.012
Yan, S., Ripamonti, R., Kawabe, H., Ben-Yehuda Greenwald, M. B. Y., & Werner, S. (2022). NEDD4-1 Is a Key Regulator of Epidermal Homeostasis and Wound Repair. J Invest Dermatol, 142(6), 1703-1713. DOI 10.1016/j.jid.2021.09.033
Yerly, L., Pich-Bavastro, C., Di Domizio, J., Wyss, T., Tissot, S., Cangkrama, M., Gilliet, M., Werner, S., & Kuonen, F. (2022). Integrated multi-omics reveals the cellular and molecular interactions governing the invasive niche in skin cancer. Nat Commun, 13, 4897. DOI 10.1038/s41467-022-32670-w
Zhou, J., Rasmussen, N.L., Olsvik, H.L., Akimov, V., Hu, Z., Evjen, G., Kaeser-Pebernard, S., Sankar, D.S., Roubaty, C., Verlhac, P., van de Beck, N., Reggiori, F., Abudu, Y.P., Blagoev, B., Lamark, T., Johansen, T. & Dengjel, J. (2022). TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1. J Cell Biol, 222(2), p.e202108144. DOI 10.1083/jcb.202108144
Aronoff, M. R., Hiebert, P., Hentzen, N. B., Werner, S., & Wennemers, H. (2021). Imaging and targeting LOX-mediated tissue remodeling with a reactive collagen peptide. Nat Chem Biol, 17, 865-871. DOI 10.1038/s41589-021-00830-6
Bernasconi, R., Thriene, K., Romero‐Fernández, E., Gretzmeier, C., Kühl, T., Maler, M., Nauroy, P., Kleiser, S., Rühl-Muth, A.-C., Stumpe, M., Kiritsi, D., Martin, S.F., Hinz, B., Bruckner-Tuderman, L., Dengjel, J. & Nyström, A. (2021). Pro‐inflammatory immunity supports fibrosis advancement in epidermolysis bullosa: intervention with Ang‐(1‐7). EMBO Mol Med, e14392. DOI 10.15252/emmm.202114392
De Pieri, A., Korman, B. D., Jüngel, A., & Wuertz‐Kozak, K. (2021). Engineering Advanced In Vitro Models of Systemic Sclerosis for Drug Discovery and Development. Adv Biology, 5(4), 2000168. DOI 10.1002/adbi.202000168
Dudaryeva, O.Y., Bucciarelli, A., Bovone, G., Huwyler, F., Jaydev, S., Broguiere, N., al Bayati, M., Lütolf, M., and Tibbitt, M.W. 3D confinement regulates cell life and death. Adv Funct Mater, 31, 2104098. DOI 10.1002/adfm.2021040
Hennig, P., Fenini, G., Di Filippo, M., Karakaya, T., & Beer, H.-D. (2021). The Pathways Underlying the Multiple Roles of p62 in Inflammation and Cancer. Biomedicines, 9(7), 707. DOI 10.3390/biomedicines9070707
Hu, Z., Sankar, D.S., Vu, B., Leytens, A., Vionnet, C., Wu, W., Stumpe, M., Martínez-Martínez, E., Stork, B. & Dengjel, J. (2021). ULK1 phosphorylation of striatin activates protein phosphatase 2A and autophagy. Cell Rep, 36(13), 109762. DOI 10.1016/j.celrep.2021.109762
Martínez-Martínez, E., Tölle, R., Donauer, J., Gretzmeier, C., Bruckner-Tuderman, L. & Dengjel, J. (2021). Increased abundance of Cbl E3 ligases alters PDGFR signaling in recessive dystrophic epidermolysis bullosa. Matrix Biol, 1698. DOI 10.1016/j.matbio.2021.10.004
Meier-Schiesser, B., Mellett, M., Ramirez-Fort, M. K., Maul, J.-T., Klug, A., Winkelbeiner, N., Fenini, G., Schafer, P., Contassot, E. & French, L.E. (2021). Phosphodiesterase-4 inhibition reduces cutaneous inflammation and IL-1β expression in a psoriasiform mouse model but does not inhibit inflammasome activation. Int J Mol Sci, 22(23):12878. DOI 10.3390/ijms222312878
Mitamura, Y., Schulz, D., Oro, S., Li, N., Kolm, I., Lang, C.V., Ziadlou, R., Tan, G., Bodenmiller, B., Steiger, P., Marzano, A., Prost, N. de, Caudin, O., Levesque, M., Stoffel, C., Schmid-Grendelmeier, P., Maverakis, E., Akdis, C.A. and Brüggen MC (2021). Cutaneous and systemic hyperinflammation drives maculopapular drug exanthema in severely ill COVID-19 patients. Allergy, 2021;00:1-14. DOI 10.1111/all.14983
Müller, B., Mazza, E., Schiestl, C., & Elrod, J. (2021). Longitudinal monitoring and prediction of long-term outcome of scar stiffness on pediatric patients. Burns & trauma, 9, tkab028. DOI 10.1093/burnst/tkab028
Polomska, A., Gousopoulos, E., Fehr, D., Bachmann, A., Bonmarin, M., Detmar, M. & Lindenblatt, N. (2021). Development and Clinical Validation of the LymphMonitor Technology to Quantitatively Assess Lymphatic Function. Diagnostics, 11(1873), 1-14. DOI 10.3390/diagnostics11101873
Ramelyte, E., Tastanova, A., Balázs, Z., Ignatova, D., Turko, P., Menzel, U., Guenova, E., Beisel, C., Krauthammer, M., Levesque, M. P., & Dummer, R. (2021). Oncolytic virotherapy-mediated anti-tumor response: a single-cell perspective. Cancer Cell, 39(3), 394-406. DOI 10.1016/j.ccell.2020.12.022
Rebling, J., Ben-Yehuda Greenwald, M., Wietecha, M., Werner, S., & Razansky, D. (2021). Long‐Term Imaging of Wound Angiogenesis with Large Scale Optoacoustic Microscopy. Adv Sci, 2004226. DOI 10.1002/advs.202004226
Sachs, D., Wahlsten, A., Kozerke, S., Restivo, G., & Mazza, E. (2021). A biphasic multilayer computational model of human skin. Biomech Model Mechan, 20(3), 969-982. DOI 10.1007/s10237-021-01424-w
Sobecki, M., Krzywinska, E., Nagarajan, S., Audigé, A., Huỳnh, K., Zacharjasz, J., Debbache, J., Kerdiles, Y., Gotthardt, D., Takeda, N., Fandrey, J., Sommer, L., Sexl, V., & Stockmann, C. (2021). NK cells in hypoxic skin mediate a trade-off between wound healing and antibacterial defence. Nat Com, 12(1), 1-15. DOI 10.1038/s41467-021-25065-w
Tastanova, A., Ramelyte, E., Balázs, Z., Menzel, U., Beisel, C., Krauthammer, M., Dummer, R., & Levesque, M. P. (2021). Collection and preprocessing of fine needle aspirate patient samples for single cell profiling and data analysis. STAR protocols, 2(2), 100581. DOI 10.1016/j.xpro.2021.100581
Vu, B., Souza, G. R., & Dengjel, J. (2021). Scaffold-free 3D cell culture of primary skin fibroblasts induces profound changes of the matrisome. Matrix Biol Plus, 100066. DOI 10.1016/j.mbplus.2021.100066
Wahlsten, A., Rütsche, D., Nanni, M., Giampietro, C., Biedermann, T., Reichmann, E., & Mazza, E. (2021). Mechanical stimulation induces rapid fibroblast proliferation and accelerates the early maturation of human skin substitutes. Biomaterials, 273, 120779. DOI 10.1016/j.biomaterials.2021.120779
Zwicky, P., Ingelfinger, F., Silva de Melo, B. M., Ruchti, F., Schärli, S., Puertas, N., Lutz, M., Phan, T.S., Kündig, T.M., Levesque, M.P., Maul, J.-T., Schlapbach, C., Leibundgut-Landmann, S., Mundt, S. & Becher, B. (2021). IL-12 regulates type 3 immunity through interfollicular keratinocytes in psoriasiform inflammation. Sci Immunol, 6(64), eabg9012. DOI 10.1126/sciimmunol.abg9012
Babity, S., Polomska, A. K., Couture, F., Bonmarin, M., Fehr, D., Detmar, M., & Brambilla, D. (2020). Rational design of a fluorescent microneedle tattoo for minimally invasive monitoring of lymphatic function. J Control Release, 327, 350-359. DOI 10.1016/j.jconrel.2020.08.017
Bircher, K., Merluzzi, R., Wahlsten, A., Spiess, D., Simoes-Wust, A. P., Ochsenbein-Kolble, N., Deprest, R., & Mazza, E. (2020). Influence of osmolarity and hydration on the tear resistance of the human amniotic membrane. J Biomech, 98, 109419. DOI 10.1016/j.jbiomech.2019.109419
Cangkrama, M., Wietecha, M., Mathis, N., Okumura, R., Ferrarese, L., Al-Nuaimi, D., Antsiferova, M., Dummer, R., Innocenti, M., & Werner, S. (2020). A paracrine activin A-mDia2 axis promotes squamous carcinogenesis via fibroblast reprogramming. EMBO Mol Med, 12(4), e11466. DOI 10.15252/emmm.201911466
Hennig, P., Fenini, G., Di Filippo, M., & Beer, H.-D. (2020). Electrophiles Against (Skin) Diseases: More Than Nrf2. Biomolecules, 10(2). DOI 10.3390/biom10020271
Hettich, B. F., Ben-Yehuda Greenwald, M., Werner, S., & Leroux, J.-C. (2020). Exosomes for Wound Healing: Purification Optimization and Identification of Bioactive Components. Adv Sci, 7(23), 2002596. DOI 10.1002/advs.202002596
Lautenbach, G., Dobrota, R., Mihai, C., Distler, O., Calcagni, M., & Maurer, B. (2020). Evaluation of botulinum toxin A injections for the treatment of refractory chronic digital ulcers in patients with systemic sclerosis. Clin Exp Rheumatol, 38 Suppl 125(3), 154-160.
McLuckie, M., Robotti, F., Sanchez-Macedo, N., Enderlin, D., Frese, L., Cheng, P. F., Levesque, M. P., Egaña, J. T., Poulikakos, D., Ferrari, A., & Lindenblatt, N. (2020). Lipoconstruct surface topography grating size influences vascularization onset in the dorsal skinfold chamber model. Acta Biomater, 106, 136-144. DOI 10.1016/j.actbio.2020.01.050
Moser, T., Lohmeyer, Q., Meboldt, M., Distler, O., & Becker, M. O. (2020). Visual assessment of digital ulcers in systemic sclerosis analysed by eye tracking: implications for wound assessment. Clin Exp Rheumatol, 38 Suppl 125(3), 137-139. clinexprheumatol.org article 15763
Mueller, B., Elrod, J., Distler, O., Schiestl, C., & Mazza, E. (2020). On the Reliability of Suction Measurements for Skin Characterization. J Biomech Eng. DOI 10.1115/1.4047661
Mueller, B., Ruby, L., Jordan, S., Rominger, M. B., Mazza, E., & Distler, O. (2020). Validation of the suction device Nimble for the assessment of skin fibrosis in systemic sclerosis. Arthritis Res Ther, 22(1), 128. DOI 10.1186/s13075-020-02214-y
Pachera, E., Assassi, S., Salazar, G. A., Stellato, M., Renoux, F., Wunderlin, A., Blyszczuk, P., Lafyatis, R., Kurreeman, F., De Vries-Bouwstra, J., Messemaker, T., Feghali-Bostwick, C. A., Rogler, G., Van Haaften, W. T., Dijkstra, G., Oakley, F., Calcagni, M., Schniering, J., Maurer, B., Distler, J. H. W., Kania, G., Frank-Bertoncelj, M., & Distler, O. (2020). Long noncoding RNA H19X is a key mediator of TGF-beta-driven fibrosis. J Clin Invest, 130(9), 4888-4905. DOI 10.1172/JCI135439
Renoux, F., Stellato, M., Haftmann, C., Vogetseder, A., Huang, R., Subramaniam, A., Becker, M. O., Blyszczuk, P., Becher, B., Distler, J. H. W., Kania, G., Boyman, O., & Distler, O. (2020). The AP1 Transcription Factor Fosl2 Promotes Systemic Autoimmunity and Inflammation by Repressing Treg Development. Cell Rep, 31(13), 107826. DOI 10.1016/j.celrep.2020.107826
Satoh, T. K., Mellett, M., Meier-Schiesser, B., Fenini, G., Otsuka, A., Beer, H.-D., Rordorf, T., Maul, J.-T., Hafner, J., Navarini, A. A., Contassot, E., & French, L. E. (2020). IL-36gamma drives skin toxicity induced by EGFR/MEK inhibition and commensal Cutibacterium acnes. J Clin Invest. DOI 10.1172/JCI128678
Wietecha, M. S., Pensalfini, M., Cangkrama, M., Mueller, B., Jin, J., Brinckmann, J., Mazza, E., & Werner, S. (2020). Activin-mediated alterations of the fibroblast transcriptome and matrisome control the biomechanical properties of skin wounds. Nat Commun, 11(1), 2604. DOI 10.1038/s41467-020-16409-z
Elrod, J., Mueller, B., Mohr, C., Meuli, M., Mazza, E., & Schiestl, C. (2019). An effective procedure for skin stiffness measurement to improve Paediatric Burn Care. Burns, 45(5), 1102-1111. DOI 10.1016/j.burns.2019.02.004
Fox, S. C., Biedermann, T., Polak, J., Reichmann, E., Daners, M. S., & Meboldt, M. (2019). A simplified fabrication technique for cellularized high-collagen dermal equivalents. Biomed Mater, 14(4), 041001. DOI 10.1088/1748-605X/ab09c5
Fox, S. C., Polak, J., Schmid Daners, M., & Meboldt, M. (2019). Fabrication of Bioengineered Skin by Injection Molding: A Feasibility Study on Automation. SLAS Technol, 24(5), 506-514. DOI 10.1177/2472630319857966
Fox, S. C., Siallagan, D., Schmid Daners, M., & Meboldt, M. (2019). Rethinking automated skin fabrication for regeneration: adapting to commercial challenges. Current Opinion in Biomedical Engineering, 10, 165-173. DOI 10.1016/j.cobme.2019.07.001
Matei, A. E., Chen, C. W., Kiesewetter, L., Gyorfi, A. H., Li, Y. N., Trinh-Minh, T., Xu, X., Tran Manh, C., van Kuppevelt, T., Hansmann, J., Jüngel, A., Schett, G., Groeber-Becker, F., & Distler, J. H. W. (2019). Vascularised human skin equivalents as a novel in vitro model of skin fibrosis and platform for testing of antifibrotic drugs. Ann Rheum Dis, 78(12), 1686-1692. DOI 10.1136/annrheumdis-2019-216108
Michalak-Micka, K., Klar, A. S., Bottcher-Haberzeth, S., Reichmann, E., Meuli, M., & Biedermann, T. (2019). Impact of human mesenchymal cells of different body site origins on the maturation of dermo-epidermal skin substitutes. Pediatr Surg Int, 35(1), 121-127. DOI 10.1007/s00383-018-4383-5
Morel, A., Oberle, S. C., Ulrich, S., Yazgan, G., Spano, F., Ferguson, S. J., Fortunato, G., & Rossi, R. M. (2019). Revealing non-crystalline polymer superstructures within electrospun fibers through solvent-induced phase rearrangements. Nanoscale, 11(36), 16788-16800. DOI 10.1039/c9nr04432a
Polomska, A. K., Proulx, S. T., Brambilla, D., Fehr, D., Bonmarin, M., Brandli, S., Meboldt, M., Steuer, C, Vasileva T., Reinke, N., Leroux, J.-C., & Detmar, M. (2019). Minimally invasive method for the point-of-care quantification of lymphatic vessel function. JCI Insight, 4(4). DOI 10.1172/jci.insight.126515
Tuncer, E., Calçada, R. C., Zingg, D., Varum, S., Cheng, P., Freiberger, S. N., Deng, C.-X., Kleiter, I., Levesque, M. P., Dummer, R., & Sommer, L. (2019). SMAD signaling promotes melanoma metastasis independently of phenotype switching. J. Clin. Invest., 129:2702-2716. DOI 10.1172/JCI94295
Varum, S., Baggiolini, A., Zurkirchen, L., Kalender Atak, Z., Cantù, C., Marzorati, E., Bossart, R., Wouters, J., Häusel, J., Tuncer, E., Zingg, D., Veen, D., John, N., Balz, M., Levesque, M. P., Basler, K., Aerts, S., Zamboni, N., Dummer, R. & Sommer, L. (2019). Yin Yang 1 orchestrates a metabolic program required for both neural crest development and melanoma formation. Cell Stem Cell, 24:637-653. DOI 10.1016/j.stem.2019.03.011
Wahlsten, A., Pensalfini, M., Stracuzzi, A., Restivo, G., Hopf, R., & Mazza, E. (2019). On the compressibility and poroelasticity of human and murine skin. Biomech Model Mechanobiol, 18(4), 1079-1093. DOI 10.1007/s10237-019-01129-1
Mueller, B., Elrod, J., Pensalfini, M., Hopf, R., Distler, O., Schiestl, C., & Mazza, E. (2018). A novel ultra-light suction device for mechanical characterization of skin. PLoS One, 13(8), e0201440. DOI 10.1371/journal.pone.0201440
Parfejevs, V., Debbache, J., Shakhova, O., Schaefer, S. M., Glausch, M., Wegner, M., Suter, U., Riekstina, U., Werner, S., & Sommer, L. (2018). Injury-activated glial cells promote wound healing of the adult skin in mice. Nature Communications, 9, 236. DOI 10.1038/s41467-017-01488-2
Pensalfini, M., Meneghello, S., Lintas, V., Bircher, K., Ehret, A. E., & Mazza, E. (2018). The suture retention test, revisited and revised. Journal of the Mechanical Behavior of Biomedical Materials, 77, 711-717. DOI 10.1016/j.jmbbm.2017.08.021
Pensalfini, M., Weickenmeier, J., Rominger, M., Santoprete, R., Distler, O., & Mazza, E. (2018). Location-specific mechanical response and morphology of facial soft tissues. Journal of the Mechanical Behavior of Biomedical Materials, 78, 108-115. DOI 10.1016/j.jmbbm.2017.10.021
Randall, M. J., Jungel, A., Rimann, M., & Wuertz-Kozak, K. (2018). Advances in the Biofabrication of 3D Skin in vitro: Healthy and Pathological Models. Front Bioeng Biotechnol, 6, 154. DOI 10.3389/fbioe.2018.00154
Zimmerli, D., Cecconi, V., Valenta, T., Hausmann, G., Cantu, C., Restivo, G., Hafner, J., Basler, K., & Van den Broek, M. (2018). WNT ligands control initiation and progression of human papillomavirus-driven squamous cell carcinoma. Oncogene, 37(27), 3753-3762. DOI 10.1038/s41388-018-0244-x
Zingg D, Debbache J, Peña-Hernández R, Antunes AT, Schaefer SM, Cheng PF, Zimmerli D, Haeusel J, Calçada RR, Tuncer E, Zhang Y, Bossart R, Wong KK, Basler K, Dummer R, Santoro R, Levesque MP, Sommer L (2018). EZH2-mediated primary cilium deconstruction drives metastatic melanoma formation. Cancer Cell 34: 69-84. DOI 10.1016/j.ccell.2018.06.00
Klar, A. S., Biedermann, T., Michalak, K., Michalczyk, T., Meuli-Simmen, C., Scherberich, A., Meuli, M., & Reichmann, E. (2017). Human Adipose Mesenchymal Cells Inhibit Melanocyte Differentiation and the Pigmentation of Human Skin via Increased Expression of TGF-beta1. J Invest Dermatol, 137(12), 2560-2569. DOI 10.1016/j.jid.2017.06.027
Pensalfini, M., Ehret, A. E., Stüdeli, S., Marino, D., Kaech, A., Reichmann, E., & Mazza, E. (2017). Factors affecting the mechanical behavior of collagen hydrogels for skin tissue engineering. J Mech Behav Biomed, 69, 85-97. DOI 10.1016/j.jmbbm.2016.12.004
Pensalfini, M., Haertel, E., Hopf, R., Wietecha, M., Werner, S., & Mazza, E. (2017). The mechanical fingerprint of murine excisional wounds. Acta Biomater, 1-11. DOI 10.1016/j.actbio.2017.10.021