SKINTEGRITY.CH Annual Lecture 2025

Exploring different cell populations in healthy and diseased skin
 — Prof. Fiona M. Watt (EMBL Heidelberg / King's College London)

The epidermis, the outer covering of the skin, has been the subject of intense investigation for many years. Autologous sheets of cultured human epidermis have been used successfully to treat burns and other skin injuries and are an important example of cell therapy involving in vitro expanded stem cells.

Numerous experiments in culture and in mouse models have provided major insights into the nature of epidermal stem cells and the local and long-range interactions that regulate their behaviour in health and disease. The advent of single-cell transcriptomics has provided an important opportunity to validate earlier conclusions based on experimental models.

Currently, the integration of techniques that provide spatial information about different cell populations in the epidermis and underlying connective tissue is allowing us to design and carry out mechanistic studies.

The event is public and free of charge, but registration is mandatory.

Register here